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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFHX4
All Species:
5.76
Human Site:
S2374
Identified Species:
14.07
UniProt:
Q86UP3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UP3
NP_078997.3
3567
393730
S2374
K
P
K
Q
S
D
P
S
P
P
S
Q
G
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089817
3156
348587
D2040
Q
L
L
Q
Y
Q
C
D
Q
C
T
V
A
F
P
Dog
Lupus familis
XP_853266
3452
379865
A2269
T
K
P
A
L
P
L
A
S
T
S
S
D
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN2
3550
392304
S2359
K
T
K
Q
S
D
P
S
L
P
Q
G
T
K
S
Rat
Rattus norvegicus
XP_226964
3593
395739
S2398
K
T
K
Q
N
D
P
S
L
P
Q
G
I
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509863
3710
407348
P2441
K
P
K
Q
T
E
P
P
S
A
Q
P
N
Q
T
Chicken
Gallus gallus
O73590
3573
394529
S2362
P
K
P
N
E
T
I
S
K
Q
T
D
T
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684360
2686
299027
Q1570
L
N
N
S
L
P
P
Q
M
L
Q
Y
H
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393785
2962
326678
A1846
P
P
P
Y
D
G
T
A
T
G
Y
P
P
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798150
3296
366823
A2180
A
A
A
A
A
A
A
A
A
A
A
A
Q
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.1
90.4
N.A.
90.8
91.8
N.A.
55.3
90.2
N.A.
52.6
N.A.
N.A.
21.1
N.A.
26
Protein Similarity:
100
N.A.
87.6
92.4
N.A.
94.1
94.9
N.A.
68.1
94
N.A.
61.7
N.A.
N.A.
36.2
N.A.
41.1
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
53.3
46.6
N.A.
33.3
13.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
N.A.
20
13.3
N.A.
53.3
53.3
N.A.
46.6
20
N.A.
13.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
20
10
10
10
30
10
20
10
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% C
% Asp:
0
0
0
0
10
30
0
10
0
0
0
10
10
0
0
% D
% Glu:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
10
0
20
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% I
% Lys:
40
20
40
0
0
0
0
0
10
0
0
0
0
20
10
% K
% Leu:
10
10
10
0
20
0
10
0
20
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
10
10
10
10
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
20
30
30
0
0
20
50
10
10
30
0
20
10
10
20
% P
% Gln:
10
0
0
50
0
10
0
10
10
10
40
10
10
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
20
0
0
40
20
0
20
10
0
0
30
% S
% Thr:
10
20
0
0
10
10
10
0
10
10
20
0
20
20
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _